Team McCallum

R&D for Lifetime of Life

Clock controls eating habits.

Professor Paul Hardin reports in Cell Biology on a clock mechanism that controls eating habits. While the study was done on fruit flies, Professor Hardin is confident a similar mechanism will exist in humans.

The team found that there are circadian (time of day) cycles in the sensitivity of taste receptors, and that this sensitivity drives feeding behaviour, by telling the brain to eat or not to eat.

These taste-based circadian clocks run independently of other clocks. Since they are quite separate, they control feeding behaviour.

The team established the mechanics as molecular clocks driving rhythms in G protein-coupled receptor kinase 2 (GPRK2) driving taste sensitivity.

Professor Hardin also found that knocking out the taste clocks led to an increase in feeding. In other words, the clocks act to restrict feeding. In fruit flies, the increased food intake was balanced by increased activity so the flies did not get fatter.


February 22, 2010 - Posted by | Circadian rhythm, Fruit flies, Paul Hardin, Weight management

1 Comment »

  1. […] Click here for another report showing how time of day is important in diet. 0.000000 0.000000 […]

    Pingback by Full breakfast small dinner diet. « Team McCallum | April 1, 2010 | Reply

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