Team McCallum

R&D for Lifetime of Life

Probiotics and IBS.

Professor P Moayyedi and others systematically reviewed studies of probiotics in the treatment of IBS (irritable bowel syndrome).

19 random controlled trials involving 1650 patients were found, which the team assessed as being of good quality. These showed probiotics reduced IBS by about 30%, compared to a placebo.

However, there was considerable variation in results across the studies, and using mathematical tests, Moayyedi suspected that positive results were being published while negative studies were not.

The review concluded “Probiotics appear to be efficacious in IBS, but the magnitude of benefit and the most effective species and strain are uncertain.”

In an editorial on the review, Professor Philippe Marteau outlined the need for this study “Probiotics are widely consumed and the widespread advertising is often not really justified by the evidence. Many products were never studied as such and some companies use studies performed with other (and different) products for advertising even during medical conventions. Evidence of benefit is still patchy and the clinician has to take into account the variability of the strains, the doses, the quality of the trials and clinical relevance of end points.”

The review and editorial appear in the March 2010 issue of the journal Gut.


March 21, 2010 - Posted by | Health, IBD, Natural healing, P Moayyedi, Philippe Marteau, Probiotics

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