Team McCallum

R&D for Lifetime of Life

Probiotics for celiac disease.

Dr Yolanda Sanz and team at the National Spanish Research Council (CSIC) in Valencia has found in lab models that probitiotics may offer hope in celiac (coeliac) disease, with possible implications in other auto-immune diseases like type 1 diabetes.

In celiac disease, gluten in wheat/rye/barley kicks off a reaction that destroys the ability of the intestines to absorb nutrients properly.

Sanz used cells to model the intestines, then exposed these to intestinal bacteria taken from celiac sufferers, and compared this to the effects of bifidobacteria. The celiac bacteria increased inflammation, while the bifidobacteria decreased it.

The chief editor of the Journal of Leukocyte Biology, where the study appears, said “Just as some foods can lead to poor health, it’s no surprise that others can have positive effects. For people with celiac disease, this opens a line of research into new therapies that may be as accessible as a grocer’s shelf.”


April 29, 2010 - Posted by | Celiac (coeliac) disease, Probiotics, Yolanda Sanz

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