Team McCallum

R&D for Lifetime of Life

Breast cancer and HRT 1.

Dr Giske Ursin and team analysed breast cancer risk by HRT use in 57,000 women in the California State Teachers Retirement System.

Women using estrogen-only for 15 years had a 19% increased risk of breast cancer. Those on combined estrogen/progestin for 15 years had an 83% increased risk.

These risks affected women with a BMI less than 30 but not those in the obese category.

The only subtype at risk from HRT was dual-receptor positive (ER+/PR+). Other sub-types did not show any increased risk.

A recent scientific statement from the Endocrine Society concluded that estrogen/progestin hormone therapy did not cause breast cancer, but instead caused preexisting tumours to grow to a size where they became detectable.

Click here for Breast Cancer And HRT 2, which found that some types of progestin increase risk, but other types are protective.


August 11, 2010 - Posted by | BMI - body mass index, Breast cancer, Estrogen - oestrogen, Giske Ursin, Health, HRT, Obesity, Progesterone, Success

1 Comment »

  1. […] This large study reported the risks of breast cancer by type of HRT use, BMI and cancer sub-type. 0.000000 0.000000 […]

    Pingback by Breast cancer and HRT 2. « Team McCallum | August 11, 2010 | Reply

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