Team McCallum

R&D for Lifetime of Life

Omega-3 v diabetes.

Scientists have worked out how omega-3 can reverse type-2 diabetes by shutting down inflammation in obese mice.

Prof Jerrold Olefsky found that omega-3 fatty acids, particularly DHA and EPA, bound to a particular receptor (GPR120) of the immune system, which resulted in potent blocking of inflammation. As the inflammation subsided, insulin sensitivity returned and blood glucose levels came under control.

The dose of omega-3 given to the mice was enough to double the level of omega-3 in their bloodstream. The omega-3 treatment was as effective, or even more effective, than the popular insulin-sensitizing drug rosiglitazone (Avandia).

In the US, Lovaza is FDA-approved for treatment of very high triglycerides, on a daily dose of 4 capsules each containing 465mg EPA and 375mg DHA as the active ingredients.

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September 4, 2010 - Posted by | Avandia, Diabetes, Health, Jerrold Olefsky, Omega-3, Rosiglitazone, Success

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